Paraneoplastic neurological syndromes

Necrobiotic xanthogranuloma This presents as multiple sharply demarcated, indurated, non-tender dermal or subcutaneous nodules and plaques. Periorbital involvement is common. Lesions vary from violaceous to red orange, and enlarge to form infiltrative plaques that may show central atrophy. Though most of the lesions are asymptomatic, some may be pruritic or painful. Ulceration and scarring are common. Associated malignancies include multiple myeloma and lymphoproliferative disorders. Figure 8. Paraneoplastic pemphigus. pruritic, polymorphous pruritic, polymorphous bullae, and erythematous papules and plaques on the trunk. Cutaneous amyloidosis